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Frequently Asked Questions

  1. What is the CVRN?
  2. How many centers make up the CVRN?
  3. What services and opportunities does the CVRN offer to researchers?
  4. I am interested in working with the CVRN, but am new to research. How do I begin collaboration?
  5. What is the difference between a Manuscript Analysis Request, a Grant Preliminary Analysis Request, a Manuscript Draft for Review, and a Grant Proposal?
  6. Does the CVRN charge for endorsement of manuscripts or grant proposals?
  7. What are the CVRN datasets?
  8. What is the purpose of the CVRN datasets?
  9. How do I know which dataset to use?
  10. Where can I find more information on CVRN datasets?
  11. I have a new idea for cardiovascular research (which existing datasets do not cover); can I still use the CVRN services offered?
  12. How do the various committees serve the CVRN?
  13. How do I sign in to cvrn.org?
  14. Who do I contact if I still have questions?

Download CVRN FAQs
 
  1. What is the CVRN?

The Cardiovascular Research Network (CVRN) is a national research consortium and resource that leverages research expertise, populations, and data sources from 14 geographically diverse health care delivery systems (~11 million members) in the United States.  Please see http://cvrn.org/info/index.aspx for further details.

  1. How many centers make up the CVRN?

There are currently 14 CVRN centers comprised of a health care delivery system and a corresponding dedicated research entity.

  CVRN Parent Organization    

  Research Entity & Location 

  Kaiser Permanente Northern California
  (CVRN Lead Organization)

  Division of Research
  Oakland, CA

  Fallon Community Health Plan

  Meyers Primary Care Institute
  Worcester, MA

  Geisinger Health System (affiliate)

  Center for Health Studies
  Danville, PA

  Group Health

  Group Health Research Institute
  Seattle, WA

  Harvard Pilgrim Health Care and 
  Harvard Medical School (affiliate)

  Department of Population Medicine
  Boston, MA

  HealthPartners

  HealthPartners Research Foundation
  Minneapolis, MN

  Henry Ford Health System

  Center for Health Services Research
  Detroit, MI

  Kaiser Permanente Colorado

  Institute for Health Research
  Denver, CO

  Kaiser Permanente Georgia (affiliate)

  Center for Health Research Southeast
  Atlanta, GA

  Kaiser Permanente Hawaii (affiliate)

  Center for Health Research Hawaii
  Honolulu, HI

  Kaiser Permanente Northwest

  Center for Health Research
  Portland, OR

  Kaiser Permanente Southern California  

  Department of Research & Evaluation
  Pasadena, CA

  Marshfield Clinic

  Marshfield Clinic Research Foundation  
  Marshfield, WI

  Scott and White  

  Division of Research & Education
  Temple, TX

  1. What services and opportunities does the CVRN offer to researchers?
  • The CVRN offers opportunities for researchers from any institution to collaborate on multi-institutional, cardiovascular research projects by partnering with CVRN researchers to leverage robust health care-related clinical and administrative data--most of which is accessible electronically--derived from large, diverse community-based populations.
  • The CVRN will provide letters of support/endorsement for grant proposals that include CVRN collaborators and align with CVRN goals.
  • The CVRN offers a number of existing research datasets for collaboration on new cardiovascular research ideas or manuscripts. Researchers from any institution are able to suggest new grant proposals and/or manuscript analyses based on large, research-quality datasets from completed or ongoing CVRN projects using each contributing center's Virtual Data Warehouse (VDW).
  • The CVRN will review manuscript ideas and, if approved, provide analytic support  options as follows:
    1. Working directly with the lead investigator to complete analyses and report results in a timely manner
    2. Providing a scrambled, de-identified analytic dataset which will allow them to test SAS code for approved descriptive and multivariable analyses that are then run on the source analytic dataset to generate the study results.
  1. I am interested in working with the CVRN, but am new to research. How do I begin collaboration?

How to begin depends on your goals in working with the CVRN.

    1. If you are looking to collaborate on existing data for the purpose of writing new manuscripts, please go to http://cvrn.org/collaboration/datasets.aspx to learn about the CVRN datasets currently available for collaboration.  You may reach out to any of the people listed in the ‘Contacts and Other Resources’ section of each dataset description.
    2. If you are looking to conduct a new study, please see http://cvrn.org/collaboration/index.aspx.  You will need to click on the ‘Research Console Login’ hyperlink at the top of the webpage to go to the Research Console and submit a new CVRN collaborative proposal idea.  You may also contact the CVRN Director, Dr. Alan S. Go, or another member of the CVRN Executive Committee for more information or for a preliminary discussion of your proposal idea (http://cvrn.org/collaboration/application.aspx).
  1. What is the difference between a Manuscript Analysis Request, a Grant Preliminary Analysis Request, a Manuscript Draft for Review, and a Grant Proposal?
  • Manuscript Analysis Request:  This is when you have a request for proposing a data analysis based on EXISTING completed CVRN project datasets.  The results of an approved Manuscript Analysis Request will be used to develop a manuscript to submit for publication in a peer-reviewed journal.
  • Grant Preliminary Analysis Request: This is when you have a request for feasibility analysis on EXISTING CVRN datasets when considering a new CVRN grant proposal idea.  The results of an approved request in this situation will be used to develop a collaborative CVRN grant proposal.
  • Manuscript Draft for Review:  This occurs when you have a manuscript which includes a CVRN-related study or data sponsored by the CVRN that you are about to submit to a journal for publication consideration.  It is mandatory that you submit your manuscript draft to the CVRN New Proposals and Publications Committee for rapid review and to ensure that the funding agency is properly acknowledged before submission.
  • Grant Proposal: This is when you have a new collaborative CVRN grant proposal for a study you plan to submit to a funder.  The proposal includes collaborating with a CVRN site and CVRN data.  You are submitting a grant proposal request so that you can obtain CVRN endorsement of this proposal before you submit to the funder.
  1. Does the CVRN charge for endorsement of manuscripts or grant proposals?

No, endorsement of approved CVRN manuscripts and grant proposals is free of charge.

  1. What are the CVRN datasets?

Each research dataset is generated from an existing CVRN multi-site project and includes longitudinal clinical and administrative information derived from the CVRN Virtual Data Warehouse (VDW) as well as other data sources. In each dataset description provided on www.cvrn.org, you will find systematic information on the cohort assembly process (including inclusion and exclusion criteria as well as data sources), cohort characteristics, key exposure and outcome variables, existing scientific abstracts and publications, and the corresponding CVRN contacts and resources. Certain dataset descriptions may also contain additional information, such as more specific details about dataset creation processes as well as important analytic considerations.

  1. What is the purpose of the CVRN datasets?

The CVRN Datasets allow collaborators to suggest new grant proposals and/or manuscript analyses based on large, research quality datasets from completed or ongoing CVRN projects.

  1. How do I know which dataset to use?

Descriptions of each dataset are available at http://cvrn.org/collaboration/datasets.aspx. These descriptions provide information on dataset population, cohort characteristics, cohort inclusion and exclusion criteria, dataset creation steps, variables, important analytic considerations, existing scientific abstracts and publications, and corresponding CVRN contacts. Such descriptions are available to aid collaborators in determining if a dataset aligns with their aims.

  1. Where can I find more information on CVRN datasets?

Descriptions of each dataset are available at http://cvrn.org/collaboration/datasets.aspx. These descriptions provide information on dataset population, cohort characteristics, cohort inclusion and exclusion criteria, dataset creation steps, variables, important analytic considerations, existing scientific abstracts and publications, and corresponding CVRN contacts. Such descriptions are available to aid collaborators in determining if a dataset aligns with their aims.

  1. I have a new idea for cardiovascular research (which existing datasets do not cover); can I still use the CVRN services offered?

Absolutely. Please see http://cvrn.org/collaboration/index.aspx. You will need to click on the ‘Research Console Login’ hyperlink in the top right corner of the webpage to go to the Research Console and submit an idea. You may also contact the CVRN Director, Dr. Alan S. Go, or another member of the Executive Committee for more information (http://cvrn.org/collaboration/application.aspx).

  1. How do the various committees serve the CVRN?

Members of all committees listed below are representatives of CVRN Sites.

  • Steering Committee:
    • Monitors progress of CVRN core projects and CVRN Committee activities
    • Establishes guidelines and policies that will facilitate multi-site collaboration within and outside the CVRN
    • Reviews and approves proposals for new CVRN projects and manuscripts for publication
  • Executive Committee:
    • Is a subset of the Steering Committee
    • Provides overall leadership for the CVRN
    • Works with potential funders and research collaborators to establish future research directions and priorities for the CVRN
  1. How do I sign in to cvrn.org?
  • Only members may sign in to cvrn.org.  To be a member, you must be part of the Steering Committee and/or your institution must be a CVRN member site.  On www.cvrn.org, click on the hyperlink labeled “Member Login” located in the top right corner and enter your username and password.
  • If signing in to the Research Console, click on the hyperlink labeled “Research Console Login” located in the top right corner on www.cvrn.org.  On the new webpage that opens you may log in, if you have already created an account, or contact the Admin@CVRN.org to get started.
  1. Who do I contact if I still have questions?

Please send an email to Admin@CVRN.org with your questions, and we will respond within 3 business days.